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1

Catalytic Function of PLA2G6 Is Impaired by Mutations Associated with Infantile Neuroaxonal Dystrophy but Not Dystonia-Parkinsonism

Engel, Laura A., Jing, Zheng, O'Brien, Daniel E., Sun, Mengyang, Kotzbauer, Paul T., Cookson, Mark R.

Journal:

Year:

2010

Language:

english

File:

PDF, 340 KB

english, 2010

2

Validation of a new predictive risk model for mortality using Framingham Heart Study data

Massaro, Joseph M, Murabito, Joanne M, Au, Rhoda, Carnahan, Emily, Kotzbauer, Gregory R, Bynum, Julie P W, Nelson, Eugene C, Lim, Stephen S, D'Agostino, Ralph B

Journal:

Year:

2013

Language:

english

File:

PDF, 55 KB

english, 2013

3

Resonance assignments of an α-synuclein fibril prepared in Tris buffer at moderate ionic strength

Barclay, Alexander M., Dhavale, Dhruva D., Courtney, Joseph M., Kotzbauer, Paul T., Rienstra, Chad M.

Journal:

Biomolecular NMR Assignments

Year:

2018

Language:

english

File:

PDF, 1.22 MB

english, 2018

4

Kinetic of denitrification and enhanced biological phosphorous removal (EBPR) of a trickling filter operated in a sequence-batch-reactor-mode (SBR-TF)

Cramer, Michael, Tränckner, Jens, Kotzbauer, Ulrich

Journal:

Environmental Technology

Year:

2019

Language:

english

File:

PDF, 1.16 MB

english, 2019

5

Expression of neurturin, GDNF, and their receptors in the adult mouse CNS

Golden, Judith P., Baloh, Robert H., Kotzbauer, Paul T., Lampe, Patricia A., Osborne, Patricia A., Milbrandt, Jeffrey, Johnson, Eugene M.

Journal:

The Journal of Comparative Neurology

Year:

1998

Language:

english

File:

PDF, 1.04 MB

english, 1998

6

Expectations and challenges in the therapeutic use of neurotrophic factors

Paul T. Kotzbauer, David M. Holtzman

Journal:

Annals of Neurology

Year:

2006

Language:

english

File:

PDF, 142 KB

english, 2006

7

Partial deficit of pantothenate kinase 2 catalytic activity in a case of tremor-predominant neurodegeneration with brain iron accumulation

Tsao-Wei Liang, Adam C. Truax, John Q. Trojanowski, Virginia M.-Y. Lee, Matthew B. Stern, Paul T. Kotzbauer

Journal:

Movement Disorders

Year:

2006

Language:

english

File:

PDF, 106 KB

english, 2006

8

Ergonomic assessment of handle design by means of electromyography and subjective rating

Jürgen Böhlemann, Karsten Kluth, Knut Kotzbauer, Helmut Strasser

Journal:

Applied Ergonomics

Year:

1994

Language:

english

File:

PDF, 1.60 MB

english, 1994

9

Optimal promoter usage for lentiviral vector-mediated transduction of cultured central nervous system cells

Mingjie Li, Nada Husic, Ying Lin, Heather Christensen, Ibrahim Malik, Sally McIver, Christine M. LaPash Daniels, David A. Harris, Paul T. Kotzbauer, Mark P. Goldberg, B. Joy Snider

Journal:

Journal of Neuroscience Methods

Year:

2010

Language:

english

File:

PDF, 2.33 MB

english, 2010

10

Neurturin, a relative of glial-cell-line-derived neurotrophic factor

Kotzbauer, Paul T., Lampe, Patricia A., Heuckeroth, Robert O., Golden, Judith P., Creedon, Douglas J., Johnson Jr, Eugene M., Milbrandt, Jeffrey

Journal:

Year:

1996

File:

PDF, 1.05 MB

1996

11

Lewy body pathology in Alzheimer’s disease

Paul T. Kotzbauer, John Q. Trojanowski, Virginia M.-Y. Lee

Journal:

Journal of Molecular Neuroscience

Year:

2001

Language:

english

File:

PDF, 95 KB

english, 2001

12

Developmentally-regulated lectin binding in the embryonic mouse telencephalon

Nicolaos A. Flaris, Kenneth S. Shindler, Paul T. Kotzbauer, Parveen Chand, Christopher P. Ludwig, Aphrodite D. Konstantinidou, Kevin A. Roth

Journal:

Year:

1995

Language:

english

File:

PDF, 1.26 MB

english, 1995

13

Neurturin, a Novel Neurotrophic Factor, Is Localized to Mouse Chromosome 17 and Human Chromosome 19p13.3

Robert O. Heuckeroth, Paul Kotzbauer, Neal G. Copeland, Debra J. Gilbert, Nancy A. Jenkins, D.B. Zimonjic, N.C. Popescu, Eugene M. Johnson Jr., Jeffrey Milbrandt

Journal:

Year:

1997

Language:

english

File:

PDF, 244 KB

english, 1997

14

Synthesis and in vitro evaluation of α-synuclein ligands

Lihai Yu, Jinquan Cui, Prashanth K. Padakanti, Laura Engel, Devika P. Bagchi, Paul T. Kotzbauer, Zhude Tu

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 578 KB

english, 2012

15

Fibrillization of α-synuclein and tau in familial Parkinson's disease caused by the A53T α-synuclein mutation

Paul T. Kotzbauer, Benoit I. Giasson, Alexxai V. Kravitz, Lawrence I. Golbe, Margery H. Mark, John Q. Trojanowski, Virginia M.-Y. Lee

Journal:

Experimental Neurology

Year:

2004

Language:

english

File:

PDF, 806 KB

english, 2004

16

Non-classical nuclear localization signal peptides for high efficiency lipofection of primary neurons and neuronal cell lines

H. Ma, J. Zhu, M. Maronski, P.T. Kotzbauer, V.M.-Y. Lee, M.A. Dichter, S.L. Diamond

Journal:

Year:

2002

Language:

english

File:

PDF, 234 KB

english, 2002

17

Persephin, a Novel Neurotrophic Factor Related to GDNF and Neurturin

Jeffrey Milbrandt, Frederic J de Sauvage, Timothy J Fahrner, Robert H Baloh, Melanie L Leitner, Malú G Tansey, Patricia A Lampe, Robert O Heuckeroth, Paul T Kotzbauer, Kelli S Simburger, Judith P Gold

Journal:

Year:

1998

Language:

english

File:

PDF, 200 KB

english, 1998

18

Disrupted Membrane Homeostasis and Accumulation of Ubiquitinated Proteins in a Mouse Model of Infantile Neuroaxonal Dystrophy Caused by PLA2G6 Mutations

Ibrahim Malik, John Turk, David J. Mancuso, Laura Montier, Mary Wohltmann, David F. Wozniak, Robert E. Schmidt, Richard W. Gross, Paul T. Kotzbauer

Journal:

The American Journal of Pathology

Year:

2008

Language:

english

File:

PDF, 2.01 MB

english, 2008

19

Increased risk of parkinsonism associated with welding exposure

Brad A. Racette, Susan R. Criswell, Jessica I. Lundin, Angela Hobson, Noah Seixas, Paul T. Kotzbauer, Bradley A. Evanoff, Joel S. Perlmutter, Jing Zhang, Lianne Sheppard, Harvey Checkoway

Journal:

NeuroToxicology

Year:

2012

Language:

english

File:

PDF, 220 KB

english, 2012

20

A quantitative study of α-synuclein pathology in fifteen cases of dementia associated with Parkinson disease

Armstrong, Richard A., Kotzbauer, Paul T., Perlmutter, Joel S., Campbell, Meghan C., Hurth, Kyle M., Schmidt, Robert E., Cairns, Nigel J.

Journal:

Journal of Neural Transmission

Year:

2014

Language:

english

File:

PDF, 469 KB

english, 2014

21

Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

Holmes, B. B., DeVos, S. L., Kfoury, N., Li, M., Jacks, R., Yanamandra, K., Ouidja, M. O., Brodsky, F. M., Marasa, J., Bagchi, D. P., Kotzbauer, P. T., Miller, T. M., Papy-Garcia, D., Diamond, M. I.

Journal:

Proceedings of the National Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 1.49 MB

english, 2013

22

Postnatal development of survival responsiveness in rat sympathetic neurons to leukemia inhibitory factor and ciliary neurotrophic factor

Kotzbauer, Paul T., Lampe, Patricia A., Estus, Steven, Milbrandt, Jeffrey, Johnson, Eugene M.

Journal:

Year:

1994

Language:

english

File:

PDF, 6.19 MB

english, 1994

23

Clinical and Laboratory Characteristics of Disseminated Herpes Simplex Virus Infection in Neonates

Kotzbauer, D., Frank, G., Dong, W., Shore, S.

Journal:

Hospital Pediatrics

Year:

2014

Language:

english

File:

PDF, 552 KB

english, 2014

24

Correlation between decreased CSF α-synuclein and Aβ1–42 in Parkinson disease

Buddhala, Chandana, Campbell, Meghan C., Perlmutter, Joel S., Kotzbauer, Paul T.

Journal:

Neurobiology of Aging

Year:

2015

Language:

english

File:

PDF, 837 KB

english, 2015

25

Neurodegeneration associated with genetic defects in phospholipase A2

Gregory, A., Westaway, S. K., Holm, I. E., Kotzbauer, P. T., Hogarth, P., Sonek, S., Coryell, J. C., Nguyen, T. M., Nardocci, N., Zorzi, G., Rodriguez, D., Desguerre, I., Bertini, E., Simonati, A., Le

Journal:

Year:

2008

Language:

english

File:

PDF, 575 KB

english, 2008

26

Neuroinflammation and Oxidation/Nitration of -Synuclein Linked to Dopaminergic Neurodegeneration

Gao, H.-M., Kotzbauer, P. T., Uryu, K., Leight, S., Trojanowski, J. Q., Lee, V. M.-Y.

Journal:

Journal of Neuroscience

Year:

2008

Language:

english

File:

PDF, 898 KB

english, 2008

27

Persistent Lethargy, Hypothermia, and Failure to Thrive in a Neonate

Kotzbauer, D., Kaler, S. G.

Journal:

Hospital Pediatrics

Year:

2015

Language:

english

File:

PDF, 480 KB

english, 2015

28

In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformation.

Mosser, D. D., Kotzbauer, P. T., Sarge, K. D., Morimoto, R. I.

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 1.59 MB

english, 1990

29

Altered Neuronal Mitochondrial Coenzyme A Synthesis in Neurodegeneration with Brain Iron Accumulation Caused by Abnormal Processing, Stability, and Catalytic Activity of Mutant Pantothenate Kinase 2

Kotzbauer, P. T.

Journal:

Journal of Neuroscience

Year:

2005

Language:

english

File:

PDF, 475 KB

english, 2005

30

CSF proteins and resting-state functional connectivity in Parkinson disease

Campbell, M. C., Koller, J. M., Snyder, A. Z., Buddhala, C., Kotzbauer, P. T., Perlmutter, J. S.

Journal:

Year:

2015

Language:

english

File:

PDF, 779 KB

english, 2015

31

Impact of a Rapid Respiratory Panel Test on Patient Outcomes

Rogers, Beverly B., Shankar, Prabhu, Jerris, Robert C., Kotzbauer, David, Anderson, Evan J., Watson, J. Renee, O'Brien, Lauren A., Uwindatwa, Francine, McNamara, Kelly, Bost, James E.

Journal:

Archives of Pathology & Laboratory Medicine

Year:

2015

Language:

english

File:

PDF, 105 KB

english, 2015

32

Genetic Ablation of Calcium-independent Phospholipase A2 Leads to Alterations in Hippocampal Cardiolipin Content and Molecular Species Distribution, Mitochondrial Degeneration, Autophagy, and Cognitive Dysfunction

Mancuso, D. J., Kotzbauer, P., Wozniak, D. F., Sims, H. F., Jenkins, C. M., Guan, S., Han, X., Yang, K., Sun, G., Malik, I., Conyers, S., Green, K. G., Schmidt, R. E., Gross, R. W.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 3.86 MB

english, 2009

33

Synthesis, characterization, and preclinical validation of a PET radiopharmaceutical for interrogating Aβ (β-amyloid) plaques in Alzheimer’s disease

Sundaram, Guruswami SM, Dhavale, Dhruva, Prior, Julie L, Sivapackiam, Jothilingam, Laforest, Richard, Kotzbauer, Paul, Sharma, Vijay

Journal:

EJNMMI Research

Year:

2015

Language:

english

File:

PDF, 1.61 MB

english, 2015

34

Pathologic Accumulation of α-Synuclein and Aβ in Parkinson Disease Patients With Dementia

Kotzbauer, Paul T., Cairns, Nigel J., Campbell, Meghan C., Willis, Allison W., Racette, Brad A., Tabbal, Samer D., Perlmutter, Joel S.

Journal:

Archives of Neurology

Year:

2012

Language:

english

File:

PDF, 176 KB

english, 2012

35

Dopaminergic, serotonergic, and noradrenergic deficits in Parkinson disease

Buddhala, Chandana, Loftin, Susan K., Kuley, Brandon M., Cairns, Nigel J., Campbell, Meghan C., Perlmutter, Joel S., Kotzbauer, Paul T.

Journal:

Annals of Clinical and Translational Neurology

Year:

2015

Language:

english

File:

PDF, 288 KB

english, 2015

36

806

Betters, Kristina, Gillespie, Scott, Kotzbauer, David, Hebbar, Kiran

Journal:

Critical Care Medicine

Year:

2015

Language:

english

File:

PDF, 52 KB

english, 2015

37

Hemin-induced transcriptional activation of the HSP70 gene during erythroid maturation in K562 cells is due to a heat shock factor-mediated stress response.

Theodorakis, N G, Zand, D J, Kotzbauer, P T, Williams, G T, Morimoto, R I

Journal:

Molecular and Cellular Biology

Year:

1989

Language:

english

File:

PDF, 2.30 MB

english, 1989

38

Clinical And Laboratory Characteristics Of Central Nervous System Herpes Simplex Virus Infection In Neonates And Young Infants

Kotzbauer, David, Andresen, Deborah, Doelling, Nancy, Shore, Steve

Journal:

Pediatric Infectious Disease Journal

Year:

2014

Language:

english

File:

PDF, 201 KB

english, 2014

39

Using Publicly Available Data to Construct a Transparent Measure of Health Care Value: A Method and Initial Results

WEEKS, WILLIAM B., KOTZBAUER, GREGORY R., WEINSTEIN, JAMES N.

Journal:

Milbank Quarterly

Year:

2016

Language:

english

File:

PDF, 306 KB

english, 2016

40

In vitro Activation of Heat Shock Transcription Factor DNA-Binding by Calcium and Biochemical Conditions that Affect Protein Conformation

Dick D. Mosser, Paul T. Kotzbauer, Kevin D. Sarge and Richard I. Morimoto

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 1.33 MB

english, 1990

41

Fluselenamyl: A Novel Benzoselenazole Derivative for PET Detection of Amyloid Plaques (Aβ) in Alzheimer’s Disease

Sundaram, G. S. M., Dhavale, Dhruva D., Prior, Julie L., Yan, Ping, Cirrito, John, Rath, Nigam P., Laforest, Richard, Cairns, Nigel J., Lee, Jin-Moo, Kotzbauer, Paul T., Sharma, Vijay

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.30 MB

english, 2016

42

High flow nasal cannula use outside of the ICU; factors associated with failure

Betters, Kristina A., Gillespie, Scott E., Miller, Judson, Kotzbauer, David, Hebbar, Kiran B.

Journal:

Pediatric Pulmonology

Year:

2016

Language:

english

File:

PDF, 110 KB

english, 2016

43

Current status of the development of PET radiotracers for imaging alpha synuclein aggregates in Lewy bodies and Lewy neurites

Kotzbauer, Paul T., Tu, Zhude, Mach, Robert H.

Journal:

Clinical and Translational Imaging

Year:

2017

Language:

english

File:

PDF, 1.00 MB

english, 2017

44

A Sensitive Assay Reveals Structural Requirements for Alpha-Synuclein Fibril Growth

Dhavale, Dhruva D., Tsai, Christina, Bagchi, Devika P., Engel, Laura A., Sarezky, Jonathan, Kotzbauer, Paul T.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 9.47 MB

english, 2017

45

Design, synthesis, and in vitro evaluation of quinolinyl analogues for α -synuclein aggregation

Yue, Xuyi, Dhavale, Dhruva D., Li, Junfeng, Luo, Zonghua, Liu, Jialu, Yang, Hao, Mach, Robert H., Kotzbauer, Paul T., Tu, Zhude

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 1.07 MB

english, 2018

46

Chalcones and Five-Membered Heterocyclic Isosteres Bind to Alpha Synuclein Fibrils in Vitro

Hsieh, Chia-Ju, Xu, Kuiying, Lee, Iljung, Graham, Thomas J. A., Tu, Zhude, Dhavale, Dhruva, Kotzbauer, Paul, Mach, Robert H.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.26 MB

english, 2018

47

Alpha Synuclein Fibrils Contain Multiple Binding Sites for Small Molecules

Hsieh, Chia-Ju, Ferrie, John J., Xu, Kuiying, Lee, Iljung, Graham, Thomas J. A., Tu, Zhude, Yu, Jennifer, Dhavale, Dhruva, Kotzbauer, Paul, Petersson, E. James, Mach, Robert H.

Journal:

ACS Chemical Neuroscience

Year:

2018

Language:

english

File:

PDF, 1.91 MB

english, 2018

48

Radiosynthesis and in Vivo Evaluation of Two PET Radioligands for Imaging α-Synuclein

Zhang, Xiang, Jin, Hongjun, Padakanti, Prashanth, Li, Junfeng, Yang, Hao, Fan, Jinda, Mach, Robert, Kotzbauer, Paul, Tu, Zhude

Journal:

Applied Sciences

Year:

2014

Language:

english

File:

PDF, 535 KB

english, 2014

49

Are ACOs Ready to be Accountable for Medication Use?

Dubois, Robert W., Feldman, Marv, Lustig, Adam, Kotzbauer, Greg, Penso, Jerry, Pope, Scott D., Westrich, Kimberly D.

Journal:

Journal of managed care pharmacy

Year:

2014

Language:

english

File:

PDF, 624 KB

english, 2014

50

Parkinson’s disease and multiple system atrophy have distinct α-synuclein seed characteristics

Yamasaki, Tritia R., Holmes, Brandon B., Furman, Jennifer L., Dhavale, Dhruva D., Su, Bryant W., Song, Eun-Suk, Cairns, Nigel J., Kotzbauer, Paul T., Diamond, Marc I.

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 766 KB

english, 2018